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The Impact of microRNAs on Mitochondrial Function and Immunity: Relevance to Parkinson’s Disease

3 May 2023

Abstract excerpt

Parkinson's Disease (PD), the second most common neurodegenerative disorder, is characterised by the severe loss of dopaminergic neurons in the Substantia Nigra pars compacta (SNpc) and by the presence of Lewy bodies. PD is diagnosed upon the onset of motor symptoms, such as bradykinesia, resting tremor, rigidity, and postural instability. It is currently accepted that motor symptoms are preceded by non-motor...

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PMID: 37239020
DOI: 10.3390/biomedicines11051349

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