Back to search

Article

Guilu erxian glue alleviates chemotherapy-induced myelosuppression by regulating histone methylation level of p16 gene in hematopoietic stem cells

2025-03-31

Abstract excerpt

Background: Myelosuppression is a common chemotherapy-related toxicity and hematopoietic stem cells (HSCs) senescence is the main mechanism. Guilu Erxian Glue (GEG) is an effective Chinese herbal prescription for the treatment of myelosuppression in clinical, the potential mechanism needs further investigation. Objective: To explore the protective effect of GEG on HSCs during chemotherapy-induced myelosuppression...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4911d7c1-fa3f-5beb-9f08-c1ea3cd11251
DOI
10.1016/j.ctmp.2025.200213
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Guilu erxian glue alleviates chemotherapy-induced myelosuppression by regulating histone methylation level of p16 gene in hematopoietic stem cellsDOI 10.1016/j.ctmp.2025.200213
Compound shougong powder inhibits the malignant phenotype of hepatocellular carcinoma cells by targeting the DNA damage repair pathway.Semantic proximity
DNA damage caused by chemotherapy has duality, and traditional Chinese medicine may be a better choice to reduce its toxicitySemantic proximity
Epimedium protects against dyszoospermia in mice with Pex3 knockout by exerting antioxidant effects and regulating the expression level of P16Semantic proximity
Decitabine induces change of biological traits in myelodysplastic syndromes via FOXO1 activationSemantic proximity
Utilizing network pharmacology to explore potential mechanisms of YiSui NongJian formula in treating myelodysplastic syndromeSemantic proximity
Cellular senescence-associated gene IFI16 promotes HMOX1-dependent evasion of ferroptosis and radioresistance in glioblastomaSemantic proximity
WM130 preferentially inhibits hepatic cancer stem-like cells by suppressing AKT/GSK3β/β-catenin signaling pathway.Semantic proximity
Identify GADD45G as a potential target of 4-methoxydalbergione in treatment of liver cancer: bioinformatics analysis and in vivo experimentSemantic proximity
Harmine inhibits pulmonary fibrosis through regulating DNA damage repair-related genes and activation of TP53-Gadd45α pathwaySemantic proximity
Qizhu anticancer prescription enhances immunosurveillance of liver cancer cells by regulating p21-dependent secretory phenotypes.Semantic proximity
Bu-Shen-Ning-Xin decoction ameliorates premature ovarian insufficiency by suppressing oxidative stress through rno_circRNA_012284/rno_miR-760–3p/HBEGF pathwaySemantic proximity
Molecular Mechanisms Associated With Amelioration Of Radiation Induced Gastrointestinal Mucositis By Compound Kushen ExtractsSemantic proximity
Select a neighboring publication to make it the new centre.