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Intratumoral Resident Microbes Directly Participate in Resistance to EGFR-TKI Targeted Drug Therapy through Metabolism in NSCLC

2025-03-12

Abstract excerpt

EGFR-TKIs targeted therapy represents a cornerstone in the treatment of non-small cell lung cancer (NSCLC). Nonetheless, a subset of patients inevitably develops acquired resistance to EGFR-TKIs, posing a significant clinical challenge. An increasing number of evidence has documented the presence of microbial communities within tumor microenvironments, but the potential interplay between tumor-resident microbiota...

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Literature Corpus work
48e42f36-8dea-583a-9de7-6de51e80ef8c
DOI
10.1101/2025.03.12.642829
Open publication

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