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Article

A real-world evidence of sputum microbiota alterations and their association with oncogenomic changes and response to targeted therapies in patients with lung cancer.

BMC microbiology - 30 Jan 2026

Li Ting, Ye Zu-Lu, Yang Xin-Hua, He Cai-Yun, Xu Wen-Na

Abstract excerpt

OBJECTIVE: Alterations to the respiratory microbiota may contribute to lung cancer progression. This study examined real-world data to characterize sputum microbiota alterations and to assess their association with oncogenomic changes and response to targeted therapies in patients with lung cancer. METHOD: A total of 724 patients with lung cancer who underwent etiological examinations of their sputum were...

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Identifiers

PMID: 41618144
DOI: 10.1186/s12866-026-04773-7
PMCID: PMC12934093

Genes

EGFR
TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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