Article
Assessment of international MOGAD diagnostic criteria in patients with overlapping MOG-associated disease and multiple sclerosis phenotypes.
Journal of neurology - 1 Sept 2024
Manzano Giovanna S, Levy Michael, Salky Rebecca, Mateen Farrah J, Klawiter Eric C, Chitnis Tanuja, Vasileiou Eleni S, Sotirchos Elias S, Gibbons Emily, Huda Saif, Jacob Anu, Matiello Marcelo
Abstract excerpt
BACKGROUND: The clinical spectrum and diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) has evolved in the setting of an optimized anti-MOG-IgG cell-based assay and expert consensus. The McDonald criteria for MS have been revised multiple times to improve the accuracy and specificity of diagnosis on a framework based on clinical presentation, MRI findings, and CSF results. While...
Topics
- Humans
- Myelin-Oligodendrocyte Glycoprotein
- Female
- Adult
- Male
- Multiple Sclerosis
- Retrospective Studies
- Autoantibodies
- Phenotype
- Middle Aged
