Article

Polymerization of misfolded protein lowers CX3CR1 expression in human PBMCs

2020-11-25

Abstract excerpt

The CX3CR1 (chemokine (C-X3-C motif) receptor 1) expression levels on immune cells have significant importance in maintaining tissue homeostasis under physiological and pathological conditions. The factors implicated in the regulation of CX3CR1 and its specific ligand CX3CL1 (fractalkine) expression remain largely unknown. Recent studies provide evidence that host‘s misfolded proteins occurring in the forms of pol...

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Literature Corpus work: 47e6194e-99c4-56a9-9a42-d855d93350c5
DOI: 10.1101/2020.11.24.395640

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