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Multimodal Effects of CD40L Blockade in Multiple Sclerosis: Insights from Preclinical and Clinical Studies

2026-03-24

Abstract excerpt

Multiple sclerosis (MS) remains a leading cause of neurological disability, primarily due to the limited efficacy of current disease-modifying therapies in arresting progressive neurodegeneration. While peripheral lymphocyte depletion effectively manages relapsing activity, it fails to address the compartmentalized, smoldering inflammation driven by interactions between adaptive and innate immune systems within th...

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Literature Corpus work
47c385c0-ce53-5a0e-9d3c-edec99b16ed8
DOI
10.20944/preprints202603.1839.v1
Open publication

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Multimodal Effects of CD40L Blockade in Multiple Sclerosis: Insights from Preclinical and Clinical StudiesDOI 10.20944/preprints202603.1839.v1
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