Back to search

Article

Exploring the mechanism of prognostic genes associated with neuroendocrine differentiation and immunotherapy resistance in non-small cell lung cancer based on the bulk transcriptome and single cell RNA sequencing

2026-02-16

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> The challenge of immunotherapy resistance has become a current research hotspot. Previous studies showed that neuroendocrine differentiation (NED) might contribute significantly to the initiation and development of non-small cell lung cancer (NSCLC). However, the interplay between immunotherapy resistance and NED of NSCLC remains unclear. This article mainly...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
013f43fc-fd34-5a1f-9f28-3cac2db6148a
DOI
10.21203/rs.3.rs-8816614/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Exploring the mechanism of prognostic genes associated with neuroendocrine differentiation and immunotherapy resistance in non-small cell lung cancer based on the bulk transcriptome and single cell RNA sequencingDOI 10.21203/rs.3.rs-8816614/v1
Comprehensive Analysis of Prognostic Value and Immune Infiltration of ATⅡ-associated Genes in Non-small Cell Lung CancerSemantic proximity
Integrating Single-Cell RNA-seq to construct a Neutrophil prognostic model for predicting immune responses in non-small cell lung cancerSemantic proximity
Integrating Single-cell RNA-seq to construct a Neutrophil prognostic model for predicting immune responses in non-small cell lung cancerSemantic proximity
Identification of a prognostic immune-related signature for small cell lung cancer.Semantic proximity
Drug resistance related genes in lung adenocarcinoma predict patient prognosis and influence the tumor microenvironmentSemantic proximity
Molecular Subtypes and Tumor Microenvironment Characteristics of Small-Cell Lung Cancer Associated with Platinum-ResistanceSemantic proximity
Identification of biomarkers, pathways and potential therapeutic targets for EGFR-TKI resistance in non-small-cell lung cancerSemantic proximity
Subtype classification based on t cell proliferation-related regulator genes and risk model for predicting outcomes of lung adenocarcinomaSemantic proximity
Identification of Immune-Related Genes and Construction of Metastasis Prediction Model for Non-Small Cell Lung CancerSemantic proximity
Dissecting heterogeneity and immune cell populations in non-small cell lung cancer by single cell RNA sequencingSemantic proximity
Transcriptomic analysis of transformed small-cell lung cancer from EGFR-mutated lung adenocarcinoma reveals distinct subgroups and precision therapy opportunitiesSemantic proximity
Transcriptome Analysis of lncRNA-mRNA Interactions in the Non-Small Cell Lung CancerSemantic proximity
Select a neighboring publication to make it the new centre.