Article

A plant peroxisome lipase, SSD5, is required for steryl ester accumulation and activation of autoimmunity

2023-02-06

Abstract excerpt

<title>Abstract</title> <p>Excess cellular sterol is harmful in mammals and plants, but the mechanisms why are awaiting clarification. Here we find a strong autoimmune response to be associated to excess endoplasmic reticulum (ER) sterols. This was obtained by studying a plant peroxisome lipase, SSD5, required for the lesion phenotype of the Arabidopsis syntaxin mutant, <italic>pen1 syp122</italic>. SSD5 is a lip...

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Literature Corpus work: 47244ad1-d4d0-50a9-af1b-fc1ea0eeddae
DOI: 10.21203/rs.3.rs-2518144/v1

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