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Article

FMRI complexity correlates with tau-PET in Late-Onset and Autosomal Dominant Alzheimer’s Disease

2022-07-03

Abstract excerpt

Neurofibrillary tangle pathology detected with tau-PET correlates closely with neuronal injury and cognitive symptoms in Alzheimer’s disease (AD). Complexity of rs-fMRI time-series, measured by entropy values, have recently been reported to decrease with aging, APOE ε4 genotype and cognitive decline in AD. Here we hypothesize that the complexity of BOLD signals provides an index for tau-related neuronal injury an...

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Literature Corpus work
46b85709-9ac4-5c08-85f1-4ce3e3a64d24
DOI
10.1101/2022.06.29.498174
Open publication

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FMRI complexity correlates with tau-PET in Late-Onset and Autosomal Dominant Alzheimer’s DiseaseDOI 10.1101/2022.06.29.498174
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