Article

Exopolysaccharides of <i>Lactobacillus crispatus</i> mediate key balancing interactions with the vaginal mucosa

2026-02-05

Abstract excerpt

Lactobacillus crispatus is a dominant member of the healthy vaginal microbiota, yet the mechanisms by which it modulates host immunity remain poorly defined, in part due to the lack of tractable in vivo models. Here, we integrate bacterial genetics, in vitro epithelial systems, human-derived data and proteomic approach (Olink) to uncover a critical role for L. crispatus exopolysaccharides (EPS) in shaping the b...

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Literature Corpus work: 4689d267-2d4f-537c-ad8e-6bc627590fef
DOI: 10.64898/2026.02.05.703754

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