Article
Strain-level variation among vaginal Lactobacillus crispatus and Lactobacillus iners as identified by comparative metagenomics.
NPJ biofilms and microbiomes - 23 Mar 2025
Nori Sai Ravi Chandra, Walsh Calum J, McAuliffe Fionnuala M, Moore Rebecca L, Van Sinderen Douwe, Feehily Conor, Cotter Paul D
Abstract excerpt
The vaginal microbiome, a relatively simple, low diversity ecosystem crucial for female health, is often dominated by Lactobacillus spp. Detailed strain-level data, facilitated by shotgun sequencing, can provide a greater understanding of the mechanisms of colonization and host-microbe interactions. We analysed 354 vaginal metagenomes from pregnant women in Ireland to investigate metagenomic community state types...
Read the complete abstract on PubMedTopics
- Female
- Humans
- Vagina
- Lactobacillus
- Metagenomics
- Lactobacillus crispatus