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Article

Intra-individual genetic diversity of vaginal Lactobacillus crispatus revealed through citizen science-driven isolation and pangenome analysis.

Journal of applied microbiology - 2 Sept 2026

de Kreek Freek, Hertzberger Rosanne, van Eeden Fleur, Illidge Shardelice, Teunis Evert-Jan, Hanemaaijer Mark, Lievens Elke, Rienstra Fanny, Wiedhaup Deniz Er, Lisotto Paola, Butler Derek, Molenaar Douwe, Kort Remco

Abstract excerpt

AIMS: A vaginal microbiome dominated by Lactobacillus crispatus is associated with positive reproductive and sexual health outcomes, yet intra-individual genetic diversity within this species remains largely unexplored. This study characterized inter- and intra-individual genomic variation in L. crispatus strains isolated through a citizen science initiative and assessed implications for multi-strain probiotic...

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Topics

Female
Humans
Vagina
Lactobacillus crispatus
Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Citizen Science

Microbiota

Metagenome

Adult

Probiotics

Source

Identifiers

PMID: 42695976
DOI: 10.1093/jambio/lxag218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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