Article

Major Shortcomings of the First Who-Recommended RT-QPCR to 'Detect' SARS-CoV-2 and to 'Diagnose' COVID-19. NGS Provides Evidence that Successive Waves of SARS-CoV-2 Variants Lack Genomic Relationship

2022-10-26

Abstract excerpt

Introduction: For the first time in medical history, the result of a laboratory assay, here RT-qPCR, was used as the sole criterion to diagnose a disease, namely Covid-19, without any rating of clinical symptoms and to justify the implementation of population-wide non-pharmaceutical interventions during virus season.<br><br>Objectives: (1) To summarize concerns raised within the scientific community on the first W...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4682c487-8314-5489-80af-46396656b1e0
DOI: 10.2139/ssrn.4248632

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Major Shortcomings of the First Who-Recommended RT-QPCR to 'Detect' SARS-CoV-2 and to 'Diagnose' COVID-19. NGS Provides Evidence that Successive Waves of SARS-CoV-2 Variants Lack Genomic RelationshipDOI 10.2139/ssrn.4248632Read

Evaluation of a Rapid and Accessible RT-qPCR Approach for SARS-CoV-2 Variant of Concern IdentificationSemantic proximity Read

Confirming Multiplex RT-qPCR Use in COVID-19 with Next-Generation Sequencing: Strategies for Epidemiological AdvantageSemantic proximity Read

Differentiation of SARS-CoV-2 Variants Using RT-qPCRs by Targeting Recurrent Mutation Sites: A Diagnostic Laboratory Experience from Multi-Center Regional Study, August 2020-December 2021, Poland.Semantic proximity Read

Estimate False-Negative RT-PCR Rates for SARS-CoV-2: A Systematic Review and Meta-AnalysisSemantic proximity Read

A New SARS-CoV-2 Variant Poorly Detected by RT-PCR on Nasopharyngeal Samples, with High LethalitySemantic proximity Read

A new SARS-CoV-2 variant poorly detected by RT-PCR on nasopharyngeal samples, with high lethalitySemantic proximity Read

Confirming Multiplex Q-PCR Use in COVID-19 with Next Generation Sequencing: Strategies for Epidemiological AdvantageSemantic proximity Read

Evidence-Based Evaluation of PCR Diagnostics for SARS-Cov-2 and The Omicron Variants by Sanger SequencingSemantic proximity Read

Limitation of Screening of Different Variants of SARS-CoV-2 by RT-PCRSemantic proximity Read

Evaluation of a Rapid and Accessible Reverse Transcription-Quantitative PCR Approach for SARS-CoV-2 Variant of Concern Identification.Semantic proximity Read

Deepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants.Semantic proximity Read

Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.Semantic proximity Read