Article

Molecular mimicry between Trypanosoma cruzi and human β-tubulin as a potential autoimmune mechanism in Chagas disease–associated megaviscera

2025-10-15

Abstract excerpt

<title>Abstract</title> Chagas disease, caused by <italic>Trypanosoma cruzi</italic>, affects a significant proportion of patients who develop digestive and cardiac complications, including megaviscera. This pathogenesis has been associated with autoimmune mechanisms mediated by molecular mimicry. In this study, an in silico evaluation of cross reactivity of β-tubulin 1.9 of <italic>T. cruzi</italic> and the h...

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Literature Corpus work: 45b8aea7-8a6e-5427-8f4a-8d46e43b16b7
DOI: 10.21203/rs.3.rs-7586194/v1

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