Article

In-situ multiomics analysis reveals only minor genetic and epigenetic changes in human liver cancer stem cells

2021-02-16

Abstract excerpt

<title>Abstract</title> <p>Cancer stem cells (CSCs) play pivotal roles in human cancer but their genetic and epigenetic changes are still largely unknown. Here we show that human CSCs are more similar to paratumor cells in liver cancer. Using single-cell-based in-situ multiomics analysis, we found that although liver CSCs (LCSCs) from patients had some potential key genetic and epigenetic changes in their genome,...

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Literature Corpus work: 453709f0-2ae0-5ef4-af2a-b3e3d404ecbd
DOI: 10.21203/rs.3.rs-244209/v1

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