Article

Data-derived wearable digital biomarkers predict Frataxin gene expression levels and longitudinal disease progression in Friedreich’s Ataxia

2021-08-16

Abstract excerpt

<title>Abstract</title> <p>Friedreich’s ataxia (FA) is a neurodegenerative disease caused by the epigenetic repression of the <italic>Frataxin</italic> gene modulating mitochondrial activity in the brain, which has a diffuse phenotypic impact on patients’ motor behavior. Therefore, with current gold-standard clinical scales, it requires 18–24 month-long clinical trials to determine if disease-modifying therapies...

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Literature Corpus work: 4510e0af-c661-5056-af72-5327bafb1871
DOI: 10.21203/rs.3.rs-737100/v1

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