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Low-intensity pulsed ultrasound/nanomechanical force generators enhance osteogenesis of bone marrow mesenchymal stem cells through microfilaments and transient receptor potential melastatin 7 activation

2022-04-05

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Low-intensity pulsed ultrasound (LIPUS) has been reported to accelerate fresh fracture healing, but its mechanism of action is unclear and its efficacy needs to be further optimized. Ultrasound in combination with functionalized microbubbles has been shown to induce local shear forces and controllable mechanical stress in cells, amplifying the mechanical effects...

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Literature Corpus work
44d18b55-e53c-54e7-9a3b-1145764d1150
DOI
10.21203/rs.3.rs-1499743/v1
Open publication

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Low-intensity pulsed ultrasound/nanomechanical force generators enhance osteogenesis of bone marrow mesenchymal stem cells through microfilaments and transient receptor potential melastatin 7 activationDOI 10.21203/rs.3.rs-1499743/v1
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