Article
Osteogenic commitment and differentiation of human mesenchymal stem cells by low-intensity pulsed ultrasound stimulation.
Journal of cellular physiology - 1 Feb 2018
Costa Viviana, Carina Valeria, Fontana Simona, De Luca Angela, Monteleone Francesca, Pagani Stefania, Sartori Maria, Setti Stefania, Faldini Cesare, Alessandro Riccardo, Fini Milena, Giavaresi Gianluca
Abstract excerpt
Low-intensity pulsed ultrasound (LIPUS) as an adjuvant therapy in in vitro and in vivo bone engineering has proven to be extremely useful. The present study aimed at investigating the effect of 30 mW/cm2 LIPUS stimulation on commercially available human mesenchymal stem cells (hMSCs) cultured in basal or osteogenic medium at different experimental time points (7, 14, 21 days). The hypothesis was that LIPUS would...
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