Article

A validated and interpretable predictive model of cruzain inhibitors

2020-06-02

Abstract excerpt

Chagas disease affects 8–11 million people worldwide, most of them living in Latin America. Moreover, migratory phenomenon have spread the infection beyond endemic areas. Efforts for the development of new pharmacological therapies are paramount, as the pharmacological profile of the two marketed drugs currently available, nifurtimox and benznidazole, needs to be improved. Cruzain, a parasitic cysteine protease, i...

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Literature Corpus work: 446f8d5f-4c8d-5bee-8f4a-7f3a43f39f0c
DOI: 10.1101/2020.06.02.129411

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