Article

Improving the calling of non-invasive prenatal testing on 13-/18-/21-trisomy by support vector machine discrimination

2017-11-09

Abstract excerpt

With the advance of next-generation sequencing technologies, non-invasive prenatal testing (NIPT) has been developed and employed in fetal aneuploidy screening on 13-/18-/21-trisomies through detecting cell-free fetal DNA (cffDNA) in maternal blood. Although Z test is widely used in NIPT nowadays, there is still necessity to improve its accuracy for removing a) false negatives and false positives, and b) the ratio...

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Literature Corpus work: 4448dc3b-2af1-5ba0-98fc-65620973e4c8
DOI: 10.1101/216689

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