Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combined fetal fraction to analyze the Z-score accuracy of noninvasive prenatal testing for fetal trisomies 13, 18, and 21

10 Feb 2023

Abstract excerpt

OBJECTIVE: This study aims to evaluate the correlation combined fetal fraction and Z-score for fetal trisomies 13, 18, and 21 of NIPT by the semiconductor sequencing platform and further analyze the differences of different sequencing depths. METHODS: A cohort of 61,581 pregnancies were recruited for NIPT. Invasive prenatal diagnostic confirmation is recommended in all high-risk NIPT cases. Logistic regression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fetal and Pediatric Neurological Disorders
Share to Pregnancy and preeclampsia studies
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36763299
DOI: 10.1007/s10815-022-02694-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combined fetal fraction to analyze the Z-score accuracy of noninvasive prenatal testing for fetal trisomies 13, 18, and 21PMID 36763299Read ↗

Evaluation of the Z‐score accuracy of noninvasive prenatal testing for fetal trisomies 13, 18 and 21 at a single centerSemantic proximity Read ↗

Performance analysis of non-invasive prenatal testing for trisomy 13, 18, and 21: A large-scale retrospective study (2018–2021)Semantic proximity Read ↗

Clinical performance of non-invasive prenatal served as a first-tier screening test for trisomy 21, 18, 13 and sex chromosome aneuploidy in a pilot city in ChinaSemantic proximity Read ↗

Analysis of fetal fraction in non-invasive prenatal testing with low-depth whole genome sequencingSemantic proximity Read ↗

Performance evaluation of noninvasive prenatal testing on 24 chromosomes in a cohort of 118,969 pregnant women in Sichuan, ChinaSemantic proximity Read ↗

Retrospective study on NIPT or NIPT plus combined with ultrasound in screening fetal chromosomal abnormalitiesSemantic proximity Read ↗

Novel perspectives in fetal biomarker implementation for the noninvasive prenatal testingSemantic proximity Read ↗

A noninvasive prenatal test pipeline with a well-generalized machine-learning approach for accurate fetal trisomy detection using low-depth short sequence dataSemantic proximity Read ↗

Update on noninvasive prenatal testing: A review based on current worldwide researchSemantic proximity Read ↗

Clinical implementation of NIPT – technical and biological challengesSemantic proximity Read ↗

The role of non-invasive prenatal testing and ultrasound in prenatal screening of fetal chromosomal abnormalities in singleton: a retrospective studySemantic proximity Read ↗

The Clinical Application of Non-invasive Prenatal Genetic Testing in the Screening of Fetal Chromosomal DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.