Article

Regulation of ryanodine receptor RyR2 by protein-protein interactions: prediction of a PKA binding site on the N-terminal domain of RyR2 and its relation to disease causing mutations

2015-01-28

Abstract excerpt

Protein-protein interactions are the key processes responsible for signaling and function in complex networks. Determining the correct binding partners and predicting the ligand binding sites in the absence of experimental data require predictive models. Hybrid models that combine quantitative atomistic calculations with statistical thermodynamics formulations are valuable tools for bioinformatics predictions. We...

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Literature Corpus work: 435d7e2c-1bc4-5073-bdd9-3431cf6a4f6d
DOI: 10.12688/f1000research.5858.1

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Regulation of ryanodine receptor RyR2 by protein-protein interactions: prediction of a PKA binding site on the N-terminal domain of RyR2 and its relation to disease causing mutationsDOI 10.12688/f1000research.5858.1Read

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