Article

Altered Intercellular Communication and Extracellular Matrix Signaling as a Potential Disease Mechanism in Human Hypertrophic Cardiomyopathy

2021-12-23

Abstract excerpt

<h4>Objectives</h4> To understand Hypertrophic Cardiomyopathy-associated alterations in gene expression and intercellular communication at the single cell level in left ventricular outflow tract lesions. <h4>Background</h4> Human hypertrophic cardiomyopathy (HCM) is considered a disorder of the sarcomere (i.e., cardiomyocytes) but the paradoxical association of nonmyocyte phenotypes such as fibrosis, mitral valve...

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Literature Corpus work: 432f821c-60a0-58d0-bc4b-59b57aa1bece
DOI: 10.1101/2021.12.18.21268004

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