Back to search

Article

Comprehensive healthspan assessments and influence of sex as a biological variable in aging rats

2025-09-22

Abstract excerpt

Rats share a significant amount of genetic and physiological similarity with humans. Many biological processes and pathways are conserved between rats and humans, making rats a suitable model for studying various aspects of human health and disease. Using rats as an aging model offers a more ethical alternative to using larger, longer-lived animals like primates. Rats are easier to handle in laboratory settings, a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
42f497f9-8a5a-53c7-8f6e-23a085964191
DOI
10.1101/2025.09.22.677661
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Comprehensive healthspan assessments and influence of sex as a biological variable in aging ratsDOI 10.1101/2025.09.22.677661
Animal Models of Aging Research: Implications for Human Aging and Age-Related DiseasesSemantic proximity
The laboratory rat: age and body weight matterSemantic proximity
Age-related Gene Expression Signatures (AGES) in rats demonstrate early, late, and linear transcriptional changes from multiple tissuesSemantic proximity
Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple TissuesSemantic proximity
FRAR course on laboratory approaches to aging. The role of pathology in rodent experimental gerontology.Semantic proximity
Computational and digital analyses in the INSPIRE mouse cohort to define sex-specific functional determinants of biological aging.Semantic proximity
Sex Specific Differences in Response to Calorie Restriction in Skeletal Muscle of Young RatsSemantic proximity
Drugs, Nutrients, and Phytoactive Principles Improving the Health Span of Rodent Models of Human Age-Related DiseasesSemantic proximity
Molecular and physiological manifestations and measurement of aging in humansSemantic proximity
The Naked Mole-Rat: A New Long-Living Model for Human Aging ResearchSemantic proximity
Sex differences in biological aging with a focus on human studiesSemantic proximity
Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and species-specific changesSemantic proximity
Select a neighboring publication to make it the new centre.