Article

Unblocking genome editing of major animal mycoplasmas using CRISPR/Cas9 base editor systems

2022-03-09

Abstract excerpt

Mycoplasmas are minimal bacteria that infect humans, wildlife, and most economically important livestock species. Mycoplasma infections cause a large range of chronic inflammatory diseases, eventually leading to death in some animals. Due to the lack of efficient recombination and genome engineering tools, the production of mutant strains for the identification of virulence factors and the development of improved...

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Literature Corpus work: 42d01a02-0c58-5023-944f-4f2ad2347099
DOI: 10.1101/2022.03.09.483585

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