Article

Oral cancer-derived extracellular vesicles biodistribute to lymph nodes, educating the metastatic niche.

2026-04-26

Abstract excerpt

<title>Abstract</title> <p> Cancer extracellular vesicles (EVs) are crucial in establishing the tumor microenvironment (TME) and metastatic niches at distant organs. EVs of oral cancer, a major type of head and neck cancer, contribute to establishing the immunosuppressive TME and metastasis to lymph nodes (LNs). However, there have been limitations in methodology (cell culture media, in vivo tracking) and hetero...

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Literature Corpus work: 42c84897-ab64-518d-a846-fb396cd4294a
DOI: 10.21203/rs.3.rs-9255590/v1

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