Article

Genetically Engineered CXCR4-modified Exosomes for Delivery of miR-126 mimics to Macrophages Alleviate Periodontitis

2023-02-17

Abstract excerpt

Biofilm related diseases are a group of diseases that tolerant antimicrobial chemotherapies therefore refractory. Periodontitis as a non-device chronic biofilm disease induced by dental plaque, can serve as an excellent in vivo model for studying the important implications of host factors in the biofilm microenvironment. Macrophage activity is one of the key factors that modulate the progression of inflammatory de...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 42c71da7-6f14-5fbe-ae25-cb12862b5d64
DOI: 10.21203/rs.3.rs-2586621/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetically Engineered CXCR4-modified Exosomes for Delivery of miR-126 mimics to Macrophages Alleviate PeriodontitisDOI 10.21203/rs.3.rs-2586621/v1Read

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitisSemantic proximity Read

Oral Spirochete <em>Treponema denticola </em>Intraoral Infection Reveals Unique miR-133a, miR-486, miR-126-3p, miR-126-5p miRNA Expression Kinetics during PeriodontitisSemantic proximity Read

Advances in the roles and mechanisms of mesenchymal stem cell derived microRNAs on periodontal tissue regenerationSemantic proximity Read

Gli1+ Inflamm-Stem Cells Engage Extracellular Vesicles to Prime Aberrant Neutrophils for Exacerbating Periodontal ImmunopathologySemantic proximity Read

Detection of Exosomal PD-L1 RNA in Saliva of Patients With PeriodontitisSemantic proximity Read

Cationic Nanostructures for the Treatment of Inflammatory Bone LossSemantic proximity Read

MicroRNA-enriched small extracellular vesicles possess odonto-immunomodulatory properties for modulating the immune response of macrophages and promoting odontogenesisSemantic proximity Read

Human Bone Marrow Mesenchymal Stem Cell-derived Extracellular Vesicles Restore Th17/Treg Homeostasis in Periodontitis via miR-1246Semantic proximity Read

Micro RNA-146a effect on Periodontitis is Independent on OPG/RANKL AxisSemantic proximity Read

The mechanism of efferocytosis in the pathogenesis of periodontitis and its possible therapeutic strategiesSemantic proximity Read

Xenogenous implanted dental follicle stem cells promote periodontal regeneration throughinduces N2 phenotype of neutrophilsSemantic proximity Read

Mini Review Therapeutic Strategies Targeting for Biofilm and Bone InfectionsSemantic proximity Read