Mini Review Therapeutic Strategies Targeting for Biofilm and Bone Infections

Abstract excerpt

is the major pathogenic bacterium for osteomyelitis, which results in a complex inflammatory response and bone destruction. Although various antibiotics have been applied for bone infection, the emergence of drug resistance and biofilm formation significantly decrease the effectiveness of those agents. In combination with gram-positive aerobes, gram-negative aerobes and anaerobes functionally equivalent...

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• Bacterial biofilms and quorum sensing
• Infectious Diseases and Tuberculosis
• Orthopedic Infections and Treatments