Article

Oral NMDA and AMPA Modulation for Refractory Obsessive-Compulsive Symptoms in Bipolar Disorder: A Case Series of Routine Clinical Outcomes

2025-12-10

Abstract excerpt

Comorbid obsessive–compulsive symptoms in bipolar disorder remain difficult to manage because serotonin-reuptake agents can trigger mood elevation while conventional mood stabilisers seldom relieve obsessions. Rapid-acting glutamatergic interventions such as intravenous ketamine improve both mood and intrusive thinking (1,2) yet are costly and logistically demanding. We describe three consecutive adults with bipol...

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Literature Corpus work: 42a47dd2-75de-59ba-b494-452f6a45a467
DOI: 10.20944/preprints202512.0799.v1

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