Article

A unified haplotype-based method for accurate and comprehensive variant calling

2018-10-29

Abstract excerpt

Haplotype-based variant callers, which consider physical linkage between variant sites, are currently among the best tools for germline variation discovery and genotyping from short-read sequencing data. However, almost all such tools were designed specifically for detecting common germline variation in diploid populations, and give sub-optimal results in other scenarios. Here we present Octopus, a versatile haplo...

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Literature Corpus work: 421155ca-9c90-5284-a651-955a90d942f5
DOI: 10.1101/456103

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