Article

Polaris: Polarization of ancestral and derived polymorphic alleles for inferences of extended haplotype homozygosity in human populations

2024-12-08

Abstract excerpt

<h4>Summary</h4> Statistical methods that measure the extent of haplotype homozygosity on chromosomes have been highly informative for identifying episodes of recent selection. For example, the integrated haplotype score ( i HS) and the extended haplotype homozygosity (EHH) statistics detect long-range haplotype structure around derived and ancestral alleles indicative of classic and soft selective sweeps, respe...

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Literature Corpus work: 41e73b3f-fc43-500f-8690-796f9f23f19d
DOI: 10.1101/2024.12.06.627098

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