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Development of Inflammatory Bowel Disease is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice

2017-08-08

Abstract excerpt

The gut microbiome is linked to inflammatory bowel disease (IBD) severity and altered in late stage disease. However, it is unclear how gut microbial communities change over the course of IBD development, especially in regards to function. To investigate microbiome mediated disease mechanisms and discover early biomarkers of IBD, we conducted a longitudinal metagenomic investigation in an established mouse model o...

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Literature Corpus work
41a87c65-09e8-56d5-a87a-bebefd836e92
DOI
10.1101/173823
Open publication

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Development of Inflammatory Bowel Disease is Linked to a Longitudinal Restructuring of the Gut Metagenome in MiceDOI 10.1101/173823
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