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High Dietary Folic Acid Intake is Associated with Genomic instability in Peripheral Lymphocytes of Healthy Adults

2022-08-25

Abstract excerpt

Mandatory fortification of food with the synthetic folic acid (FA) was instituted in 1998 to reduce the incidence of neural tube defects. Adequate folate status is correlated with numerous health benefits. However, elevated consumption of FA is controversially associated with deleterious effects on health. We previously reported that excess FA mimicked folate depletion in a lymphoblastoid cell line. To explore the...

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Literature Corpus work
4177922e-f774-58a2-9e5f-418d760ddac9
DOI
10.20944/preprints202208.0429.v1
Open publication

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