Article

Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19

2021-11-20

Abstract excerpt

<h4>Background</h4> Immunoglobulin G1 (IgG1) effector functions are impacted by the structure of fragment crystallizable (Fc) tail-linked N -glycans. Low fucosylation levels on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein specific (anti-S) IgG1 has been described as a hallmark of severe coronavirus disease 2019 (COVID-19) and may lead to activation of macrophages via immune complexes...

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Identifiers and source

Literature Corpus work: 4156ff65-4133-5f9a-875e-d707754a09d9
DOI: 10.1101/2021.11.18.21266442

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