An exploratory study of gastrointestinal redox biomarkers in the presymptomatic and symptomatic Tg2576 mouse model of familial Alzheimer’s disease – phenotypic correlates and the effects of chronic oral D-galactose

Abstract excerpt

The gut might play an important role in the etiopathogenesis of Alzheimer’s disease (AD) as gastrointestinal alterations often precede the development of neuropathological changes in the brain and correlate with disease progression in animal models. The gut has an immense capacity to generate free radicals whose role in the etiopathogenesis of AD is well known; however, it remains to be clarified whether gastroint...

Topics

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• Alzheimer's disease research and treatments
• Diet and metabolism studies
• Ginkgo biloba and Cashew Applications
• Gut microbiota and health
• Infant Nutrition and Health
• Neurological Disease Mechanisms and Treatments
• Probiotics and Fermented Foods
• Tryptophan and brain disorders

Identifiers and source

Literature Corpus work

40b094eb-7526-5b10-8180-bd4613b89048

DOI

10.1101/2023.06.03.542513