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Microbiome Alterations and Alzheimer’s Disease: Modeling Strategies with Transgenic Mice

27 Jun 2023

Abstract excerpt

In the last decade, the role of the microbiota-gut-brain axis has been gaining momentum in the context of many neurodegenerative and metabolic disorders, including Alzheimer's disease (AD) and diabetes, respectively. Notably, a balanced gut microbiota contributes to the epithelial intestinal barrier maintenance, modulates the host immune system, and releases neurotransmitters and/or neuroprotective short-chain...

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PMID: 37509487
DOI: 10.3390/biomedicines11071846

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