Article

High-throughput microcircuit analysis of individual human brains through next-generation multineuron patch-clamp

2019-05-18

Abstract excerpt

Comparing neuronal microcircuits across different brain regions, species and individuals can reveal common and divergent principles of network computation. Simultaneous patch-clamp recordings from multiple neurons offer the highest temporal and subthreshold resolution to analyse local synaptic connectivity. However, its establishment is technically complex and the experimental performance is limited by high failur...

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Literature Corpus work: 4073aa65-8dc1-54e9-a2cc-a77ccd7cada0
DOI: 10.1101/639328

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