Analysis of immunogenic cell death in periodontitis based on scRNA-seq and bulk RNA-seq data

Abstract excerpt

Background: Recent studies have suggested that cell death may be involved in bone loss or the resolution of inflammation in periodontitis. Immunogenic cell death (ICD), a recently identified cell death pathway, may be involved in the development of this disease. Methods: By analyzing single-cell RNA sequencing (scRNA-seq) for periodontitis and scoring gene set activity, we identified cell populations associated...

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