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Article

L-DOPA treatment promotes sustained neurovascular and synaptic homeostasis in the diabetic retina

2026-02-18

Abstract excerpt

While previous work has shown a sustained protective effect of levodopa (L-DOPA) on retinal function in early-stage diabetic retinopathy (DR) in humans, its underlying biology is unknown. Using noninvasive measures in diabetic mice, we found L-DOPA protects retinal neurovascular function as measured by oscillatory potential timing and flicker-evoked retinal vasodilation, as well as visual behavior, for at least tw...

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Literature Corpus work
4013c449-5e83-5743-b271-5b428cedfbeb
DOI
10.64898/2026.02.17.706466
Open publication

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L-DOPA treatment promotes sustained neurovascular and synaptic homeostasis in the diabetic retinaDOI 10.64898/2026.02.17.706466
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