Article
OPTIMIR, a novel algorithm for integrating available genome-wide genotype data into miRNA sequence alignment analysis
2018-11-27
Abstract excerpt
Next-generation sequencing is an increasingly popular and efficient approach to characterize the full set of microRNAs (miRNAs) present in human biosamples. MiRNAs’ detection and quantification still remain a challenge as they can undergo different post transcriptional modifications and might harbor genetic variations (polymiRs) that may impact on the alignment step. We present a novel algorithm, OPTIMIR, that inc...
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Identifiers and source
- Literature Corpus work
- 3f86d4f1-722b-569f-a424-afcf1b27a548
- DOI
- 10.1101/479097