Article

Virtual Responsive Neurostimulation Implantation: From Intracranial Connectivity to Optimized Lead Placement

2026-06-22

Abstract excerpt

Responsive neurostimulation (RNS) is an implanted device that delivers direct brain stimulation for drug-resistant focal epilepsy. Individual responses are highly variable, and no validated framework exists to predict outcome or guide lead placement before implantation. We hypothesized that this variability is partly explained by lead placement in relation to patterns of functional connectivity in brain networks....

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Literature Corpus work: 3f5ea42d-bff0-517b-96a3-2b98676ea5da
DOI: 10.64898/2026.06.17.26355892

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