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Copper-Based Targeted Nanozyme Platform with Sequential Phototherapy-Enzymatic Therapy for Orchestrating Macrophage Homeostasis in Rheumatoid Arthritis

2026-07-27

Abstract excerpt

<title>Abstract</title> <p>Rheumatoid arthritis (RA) remains a formidable clinical challenge due to the vicious cycle of hyperactivated M1 macrophages, excessive reactive oxygen species (ROS), and sustained pro-inflammatory cytokine storm. Herein, we rationally engineer a targeted copper-based nanozyme platform (CPPF NPs) with sequential dual-wavelength phototherapy-enzymatic activities for spatiotemporally contr...

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Literature Corpus work
3f2b48dc-9018-5625-a59c-12ffb06178d2
DOI
10.21203/rs.3.rs-10346257/v1
Open publication

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Copper-Based Targeted Nanozyme Platform with Sequential Phototherapy-Enzymatic Therapy for Orchestrating Macrophage Homeostasis in Rheumatoid ArthritisDOI 10.21203/rs.3.rs-10346257/v1
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