Article

Chances and challenges of machine learning based disease classification in genetic association studies illustrated on age-related macular degeneration

2019-12-08

Abstract excerpt

Imaging technology and machine learning algorithms for disease classification set the stage for high-throughput phenotyping and promising new avenues for genome-wide association studies (GWAS). Despite emerging algorithms, there has been no successful application in GWAS so far. We established machine learning based disease classification in genetic association analysis as a misclassification problem. To evaluate...

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Literature Corpus work: 3f078ff9-cf81-5651-8073-a3b7f54d9f12
DOI: 10.1101/867697

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