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Article

Oncocytic intraductal carcinoma of salivary glands: a distinct variant with TRIM33-RET fusions and BRAF V600E mutations.

Histopathology - 1 Sept 2021

Bishop Justin A, Nakaguro Masato, Whaley Rumeal D, Ogura Kanako, Imai Hiroshi, Laklouk Israa, Faquin William C, Sadow Peter M, Gagan Jeffrey, Nagao Toshitaka

Abstract excerpt

AIMS: Salivary gland intraductal carcinoma (IDC) is a complex ductal neoplasm surrounded by a layer of myoepithelial cells. Recent insights have shown that there are three different types: intercalated duct-like, with frequent NCOA4-RET fusions; apocrine, with salivary duct carcinoma-like mutations; and mixed intercalated duct-like/apocrine, with RET fusions, including TRIM27-RET. In addition, an oncocytic IDC...

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Share to Carcinoma, Ductal
Share to Carcinoma, Intraductal, Noninfiltrating

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diagnosis, Differential

Share to In Situ Hybridization, Fluorescence

Share to Proto-Oncogene Proteins c-ret

Share to Salivary Gland Neoplasms

Share to Salivary Glands

Share to Sequence Analysis, RNA

Source

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Identifiers

PMID: 33135196
DOI: 10.1111/his.14296
PMCID: PMC8315294

Provenance

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