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Article

Sclerosing Polycystic Adenoma of Salivary Glands: A Novel Neoplasm Characterized by PI3K-AKT Pathway Alterations-New Insights Into a Challenging Entity.

The American journal of surgical pathology - 1 Feb 2022

Skálová Alena, Baněčková Martina, Laco Jan, Di Palma Silvana, Agaimy Abbas, Ptáková Nikola, Costes-Martineau Valérie, Petersson Bengt F, van den Hout Mari F C M, de Rezende Gisele, Klubíčková Natálie, Koblížek Miroslav, Koshyk Olena, Vaneček Tomáš, Leivo Ilmo

Abstract excerpt

Sclerosing polycystic adenoma (SPA) is a rare salivary gland neoplasm originally thought to represent a non-neoplastic lesion. Recently we have encountered an index case of apocrine intraductal carcinoma of parotid gland of 62-year-old man with invasive salivary duct carcinoma component arising from SPA, a combination of tumor entities that has never been published so far. Here, we further explore the nature of...

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PMID: 34510113
DOI: 10.1097/PAS.0000000000001807

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