Article

Anti-fibrotic effect of Smad Decoy Oligodeoxynucleotide in CCl<sub>4</sub>-Induced Hepatic Fibrosis Animal Model

2018-06-30

Abstract excerpt

Hepatic fibrosis is the wound-healing process of chronic hepatic disease that leads to end-stage of hepatocellular carcinoma and demolition of hepatic structures. EMT has been identified to phenotypic conversion of the epithelium to mesenchymal phenotype that occurred during fibrosis. Smad decoy oligodeoxynucleotide (ODN) is a synthetic DNA fragment containing complementary sequence of Smad transcription factor. T...

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Literature Corpus work: 3e7d06fb-f171-587e-992d-d443d7c2bf28
DOI: 10.20944/preprints201806.0497.v1

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