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Article

Biomarker-Defined Phenotyping Reveals Patient Heterogeneity Not Captured by a Single Physiological Reserve Score

2026-08-25

Abstract excerpt

<h4>Background: </h4> Patient heterogeneity in routine biomarkers is often collapsed into a single physiological reserve score, but whether that one-dimensional representation holds across acute and chronic settings — or whether it obscures biomarker-defined subgroups relevant to individualized care — is unclear. <h4>Methods:</h4> We harmonized routine biomarkers (BMI, blood pressure, eGFR, LDL and total cholester...

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Literature Corpus work
3e309988-c16b-560a-b729-a034de66c786
DOI
10.20944/preprints202608.1744.v1
Open publication

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Biomarker-Defined Phenotyping Reveals Patient Heterogeneity Not Captured by a Single Physiological Reserve ScoreDOI 10.20944/preprints202608.1744.v1
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