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SEPT2 Protein Crotonylation Promotes Metastasis and Recurrence Through AKT Pathway in Hepatocellular Carcinoma and is Associated with Poor Survival

2022-02-24

Abstract excerpt

<h4>Background: </h4> Hepatocellular carcinoma (HCC) metastasis and recurrence lead to therapy failure. Posttranslational modification (PTM) mechanisms in HCC, especially those of recently discovered PTMs, such as lysine crotonylation (Kcr), are still poorly understood. Methods Kcr protein levels in HCC cell lines of MHCC-97H (highly invasive) cells and MHCC-97L (minimally invasive) were detected through stable i...

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Literature Corpus work: 3e1c272c-41fb-5820-a813-dec4afb18cd4
DOI: 10.21203/rs.3.rs-1378697/v1

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