Article

RNA sequencing identifies lung cancer lineage and facilitates drug repositioning

2023-01-18

Abstract excerpt

Breakthrough therapies recently improve survival in lung adenocarcinoma (LUAD), yet we still lack a paradigm to support prospective confirmation. To classify three clusters including bronchioid, neuroendocrine, and squamoid, the non-negative matrix factorization (NMF) algorithm was first performed at The Cancer Genome Atlas (TCGA), Clinical Proteomic Tumor Analysis Consortium (CPTAC), Gene Expression Omnibus (GEO)...

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Literature Corpus work: 3d850ebd-51ca-5f57-9282-0ce2e6a89d15
DOI: 10.1101/2023.01.18.524544

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